منابع مشابه
Switching acute coronary syndrome patients from prasugrel to clopidogrel.
OBJECTIVES This study sought to assess the consequences of switching prasugrel to clopidogrel on platelet inhibition and clinical outcomes after an acute coronary syndrome (ACS). BACKGROUND Many ACS patients are switched from prasugrel to clopidogrel within the recommended 1-year duration of treatment. METHODS Platelet reactivity was measured with the VerifyNow P2Y(12) assay (Accumetrics, S...
متن کاملIncreased platelet inhibition after switching from maintenance clopidogrel to prasugrel in Japanese patients with stable coronary artery disease.
BACKGROUND The pharmacodynamic effects of changing from standard-dose clopidogrel to low-dose (3.75 mg) prasugrel in Japanese patients are largely unknown. METHODSANDRESULTS A total of 53 consecutive Japanese patients with stable coronary artery disease (CAD) who received aspirin and clopidogrel were enrolled. Clopidogrel was switched to 3.75 mg prasugrel. At day 14, prasugrel was switched to...
متن کاملManagement of a hypersensitivity reaction to thienopyridines: prasugrel-induced fever and hepatitis resolved after switching to clopidogrel.
other trigger factors also could have promoted the TTC: the cesarean delivery itself or the oxytocin infusion, which induced a junctional tachycardia with myocardial ischemia. However, the delay between the stressful trigger and the first symptom is usually less than 2 h in the published cases of TTC after cesarean delivery. Moreover, our patient became transiently asymptomatic when the junctio...
متن کاملIncreased platelet inhibition after switching from maintenance clopidogrel to prasugrel in patients with acute coronary syndromes: results of the SWAP (SWitching Anti Platelet) study.
OBJECTIVES The objective was to evaluate the pharmacodynamic response of switching patients on maintenance phase clopidogrel therapy after an acute coronary syndrome (ACS) to prasugrel. BACKGROUND Prasugrel P2Y(12) receptor blockade is associated with greater pharmacodynamic platelet inhibition and reduction of ischemic complications compared with that of clopidogrel in ACS patients undergoin...
متن کاملSwitching from ticagrelor to clopidogrel: New answers and further questions.
Thromb Haemost 2017; 117: 303–310 Switching antiplatelet therapies is a common occurrence in clinical practice (1). The current availability of different oral P2Y12 receptor antagonists allows for multiple treatment options and has raised questions on the optimal approach if switching among these therapies is needed or desired. Despite the evidence for sustained efficacy and safety of ticagrelo...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Interventions
سال: 2013
ISSN: 1936-8798
DOI: 10.1016/j.jcin.2012.12.001